Electroencephalogram alterations associated with psychiatric disorders in temporal lobe epilepsy with mesial sclerosis: A systematic review

Temporal lobe epilepsy (TLE) is the most frequent focal epilepsy in adults and has been associated with psychiatric disorders (PD), especially the TLE with mesial temporal sclerosis (MTS). Electroencephalogram (EEG) could help in locating the epileptogenic zone and supply information regarding cereb...

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Bibliographic Details
Published in:Epilepsy & behavior 2020-07, Vol.108, p.107100-107100, Article 107100
Main Authors: de Barros Lourenço, Fabiani Honorato, Marques, Lucia Helena Neves, de Araujo Filho, Gerardo Maria
Format: Article
Language:English
Subjects:
Databases, Factual
Electroencephalography
Electroencephalography - methods
Electroencephalography - trends
Epilepsy
Epilepsy, Temporal Lobe - diagnosis
Epilepsy, Temporal Lobe - physiopathology
Epilepsy, Temporal Lobe - psychology
Female
Humans
Male
Mental disorders
Mental Disorders - diagnosis
Mental Disorders - physiopathology
Mental Disorders - psychology
Temporal lobe
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Summary:Temporal lobe epilepsy (TLE) is the most frequent focal epilepsy in adults and has been associated with psychiatric disorders (PD), especially the TLE with mesial temporal sclerosis (MTS). Electroencephalogram (EEG) could help in locating the epileptogenic zone and supply information regarding cerebral electric activity in these patients. However, there is a scarcity of knowledge about the association between EEG findings and comorbid PD in TLE. The objective of this review was to proceed a systematic review about the association of interictal EEG findings and PD in patients with TLE-MTS. A PRISMA model was used, and MEDLINE, CENTRAL, LILACS, and CAPES databases were searched. Six articles were considered in this review based on the inclusion/exclusion criteria. Results showed few published studies and contradicting conclusions regarding the association of EEG and PD in TLE-MTS. We observed great heterogeneity regarding the populations analyzed, hindering the comparison between the studies found. Studies with greater methodological robustness are needed to better understand the role of EEG as a possible biomarker for PD in TLE-MTS. •There are few studies about EEG x psychiatric disorders in Temporal Lobe Epilepsy with mesial sclerosis•Left temporal lobe epileptiform discharges and infrequent epileptiform discharges seems to be associated with mood disorders in Temporal Lobe Epilepsy•The findings on EEG in post-ictal psychosis in Temporal Lobe Epilepsy are contradictory•Clinical studies with greater methodological rigor are needed to understand the relation of EEG and psychiatric disorders in Temporal Lobe Epilepsy
ISSN:1525-5050
1525-5069
DOI:10.1016/j.yebeh.2020.107100