Post–Left Atrium Space Index in Fetuses With Total Anomalous Pulmonary Venous Connection and Other Congenital Heart Diseases

• Published in: Journal of ultrasound in medicine 2020-12, Vol.39 (12), p.2405-2412
• Main Authors: Han, Jiancheng, Li, Tianjing, Wu, Wenfang, Zhang, Ye, Liu, Xiaowei, Gu, Xiaoyan, Sun, Lin, Gao, Shuang, He, Yihua
• Format: Article
• Language: English
• Subjects: congenital heart defect; Female; fetal echocardiogram; Fetus; Heart Atria - diagnostic imaging; Heart Defects, Congenital - diagnostic imaging; Humans; post–left atrium space index; Pregnancy; prenatal diagnosis; Pulmonary Veins - diagnostic imaging; Retrospective Studies; total anomalous pulmonary venous connection; Ultrasonography, Prenatal
• ISSN: 0278-4297; 1550-9613
• DOI: 10.1002/jum.15362

Objectives We aimed to explore the value of the post–left atrium space (PLAS) index in the diagnosis of total anomalous pulmonary venous connection (TAPVC) and the effect of other congenital heart diseases on the PLAS index in the fetus. Methods The PLAS index of 69 fetuses with TAPVC was analyzed retrospectively. Approximately 252 healthy fetuses were randomly selected as controls, and 110 cases of intracardiac malformations were randomly selected for comparison. The PLAS index was defined as the ratio of the left atrium–descending aorta distance divided by the descending aorta diameter from the 4‐chamber view in the end‐systolic phase. Results There were no significant differences in the PLAS index among the 3 groups of isolated TAPVC subtypes (P > .05), or among the isolated TAPVC group and the simple and complex cardiac anomaly groups (P > .05). Compared with the control group, the PLAS index of the TAPVC group was significantly increased (P