Sustainability of a Clinical Examination-Based Approach for Ascertainment of Early-Onset Sepsis in Late Preterm and Term Neonates

We demonstrated the sustained impact over a 5-year period of a clinical examination-based approach to identification of early-onset sepsis in late preterm and term neonates at our hospital. To date, more than 20 000 neonates have been safely managed using this approach, resulting in a 63% reduction...

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Bibliographic Details
Published in:The Journal of pediatrics 2020-10, Vol.225, p.263-268
Main Authors: Frymoyer, Adam, Joshi, Neha S., Allan, Jessica M., Cohen, Ronald S., Aby, Janelle L., Kim, Juliann L., Benitz, William E., Gupta, Arun
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - therapeutic use
antibiotics
antimicrobial stewardship
Cohort Studies
Female
Humans
Infant, Newborn
Infant, Premature
Interrupted Time Series Analysis
Neonatal Screening - methods
Neonatal Sepsis - diagnosis
Neonatal Sepsis - drug therapy
Pregnancy
Quality Improvement
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Summary:We demonstrated the sustained impact over a 5-year period of a clinical examination-based approach to identification of early-onset sepsis in late preterm and term neonates at our hospital. To date, more than 20 000 neonates have been safely managed using this approach, resulting in a 63% reduction in antibiotic use.
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2020.05.055