Increased IL-8 levels in HIV-infected individuals who initiated ART with CD4+ T cell counts <350 cells/mm3 – A potential hallmark of chronic inflammation

The identification of inflammatory markers in HIV+ individuals on ART is fundamental since chronic ART-controlled HIV infection is linked to an increased inflammatory state. In this context, we assessed plasma levels of pro-inflammatory cytokines (IL-1β, IL-8, and IL-12p70) of HIV+ individuals who i...

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Bibliographic Details
Published in:Microbes and infection 2020-10, Vol.22 (9), p.474-480
Main Authors: Ellwanger, Joel Henrique, Valverde-Villegas, Jacqueline María, Kaminski, Valéria de Lima, de Medeiros, Rúbia Marília, Almeida, Sabrina Esteves de Matos, Santos, Breno Riegel, de Melo, Marineide Gonçalves, Hackenhaar, Fernanda Schäfer, Chies, José Artur Bogo
Format: Article
Language:English
Subjects:
AIDS
HIV
Inflammation
Interleukin 1β
Interleukin 8
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Summary:The identification of inflammatory markers in HIV+ individuals on ART is fundamental since chronic ART-controlled HIV infection is linked to an increased inflammatory state. In this context, we assessed plasma levels of pro-inflammatory cytokines (IL-1β, IL-8, and IL-12p70) of HIV+ individuals who initiated ART after immunosuppression (CD4+ T cell counts
ISSN:1286-4579
1769-714X
1769-714X
DOI:10.1016/j.micinf.2020.05.019