A novel peroxidase/oxidase mimetic Fe‐porphyrin covalent organic framework enhanced the luminol chemiluminescence reaction and its application in glucose sensing

A Fe‐porphyrin covalent organic framework (Fe‐PorCOF) was prepared through a postmodification strategy and characterized using different techniques. Fe‐PorCOF exhibits an inherent peroxidase/oxidase mimetic catalytic activity and sharply accelerates chemiluminescence (CL) reactions between luminol a...

Full description

Saved in:
Bibliographic Details
Published in:Luminescence (Chichester, England) England), 2020-12, Vol.35 (8), p.1366-1372
Main Authors: Zhao, Yaxin, Xu, Xiaotong, Ma, Yuyu, Tan, Haonan, Li, Yinhuan
Format: Article
Language:English
Subjects:
Catalysts
Catalytic activity
Chemical activity
Chemiluminescence
Chemoreception
Detection
Dissolved oxygen
Fe‐porphyrin covalent organic framework
Glucose
Glucose oxidase
Hydrogen peroxide
Iron
oxidase mimetic
Oxidation
Peroxidase
peroxidase mimetic
Porphyrins
Reactive oxygen species
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A Fe‐porphyrin covalent organic framework (Fe‐PorCOF) was prepared through a postmodification strategy and characterized using different techniques. Fe‐PorCOF exhibits an inherent peroxidase/oxidase mimetic catalytic activity and sharply accelerates chemiluminescence (CL) reactions between luminol and hydrogen peroxide (H2O2) or dissolved oxygen (O2) under alkaline conditions. The catalytic role was attributed to a significant increase in production of reactive oxygen species. Using the imminent peroxidase mimetic catalytic activity of Fe‐PorCOF, a new CL method was developed for determination of H2O2 over a linear range from 0.01 to 10.0 μmol·L−1 and with a limit of detection of 5.3 nmol·L−1. The combination of the peroxidase mimetic catalytic activity of Fe‐PorCOF with the catalytic activity of glucose oxidase on glucose oxidation presents a sensitive CL method for glucose assay. The linear range and the detection limit for glucose were 0.05–8.0 μmol·L−1 and 4.0 nmol·L−1, respectively. The practicability of this method was assessed by determination of glucose in human sera. As a peroxidase/oxidase mimetic, Fe‐PorCOF is easy to prepare and exhibits good catalytic efficiency in the luminol reaction. We believe that this strategy will promote the development of a CL field with functional COFs as a catalyst.
ISSN:1522-7235
1522-7243
DOI:10.1002/bio.3899