Of dots and levels: a case of partial subacute combined degeneration

Subacute combined degeneration of the spinal cord is a typical clinical syndrome due to vitamin B12 deficiency, characterised by the involvement of the posterior column and corticospinal tracts. Occasionally, it may present with atypical features such as a sensory level and Lhermitte's sign, bo...

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Bibliographic Details
Published in:Tropical doctor 2020-10, Vol.50 (4), p.367-368
Main Authors: Garg, Divyani, George, Jerry A, Dhamija, Rajinder K
Format: Article
Language:English
Subjects:
Adult
Humans
Magnetic Resonance Imaging
Male
Neurologic Examination
Spinal Cord - diagnostic imaging
Spinal Cord - pathology
Spinal Cord - physiopathology
Subacute Combined Degeneration - blood
Subacute Combined Degeneration - diagnosis
Subacute Combined Degeneration - pathology
Subacute Combined Degeneration - physiopathology
Vitamin B 12 Deficiency - blood
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Summary:Subacute combined degeneration of the spinal cord is a typical clinical syndrome due to vitamin B12 deficiency, characterised by the involvement of the posterior column and corticospinal tracts. Occasionally, it may present with atypical features such as a sensory level and Lhermitte's sign, both traditionally considered to be a feature of compressive myelopathy. Spinal magnetic resonance imaging strongly augments the diagnosis by exhibiting changes in the posterior column in the form of a ‘dot’. We describe such a patient who responded to therapy.
ISSN:0049-4755
1758-1133
DOI:10.1177/0049475520932201