3D microcalcification detection using a color Doppler twinkling artifact with optimized transmit conditions: Preliminary results

Purpose Mammography is the only method that has been proven to detect breast microcalcifications (MCs), but the sensitivity of mammography varies according to breast density. This paper proposes an ultrasound (US) color Doppler twinkling artifact (CDTA) method with optimized transmit conditions to i...

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Bibliographic Details
Published in:Medical physics (Lancaster) 2020-12, Vol.47 (12), p.6171-6178
Main Authors: Kang, Jinbum, Han, Kanghee, Kim, Kang‐Sik, Jang, Won Seuk, Kim, Min Jung, Yoo, Yangmo
Format: Article
Language:English
Subjects:
3D volume reconstruction
Breast Diseases
Calcinosis - diagnostic imaging
color Doppler twinkling artifact
human breast surgical specimen
Humans
Mammography
microcalcification
Phantoms, Imaging
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Summary:Purpose Mammography is the only method that has been proven to detect breast microcalcifications (MCs), but the sensitivity of mammography varies according to breast density. This paper proposes an ultrasound (US) color Doppler twinkling artifact (CDTA) method with optimized transmit conditions to identify breast MCs without ionizing radiation. Methods The transmit conditions for US color Doppler imaging (CDI) were optimized to enhance the sensitivity of the twinkling artifact (TA) that arises from random scattering on rough surfaces of breast MCs. To validate the proposed breast MC detection method, a chicken breast phantom with MC particles (groups of particles
ISSN:0094-2405
2473-4209
DOI:10.1002/mp.14342