Illuminating Neuroimmunity: A Humoral Brain

The hypothalamic-pituitary-adrenal axis modulates immunity in response to stress. In a recent report in the May 14, 2020 issue of Nature, Zhang et al. use optogenetic tools to investigate whether the splenic immune response is directly controlled by descending neuronal circuits activated in response...

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Bibliographic Details
Published in:Immunity (Cambridge, Mass.) Mass.), 2020-06, Vol.52 (6), p.900-902
Main Authors: Haberman, Emma R., Domingos, Ana I.
Format: Article
Language:English
Subjects:
Ablation
Bone marrow
Brain
Ethanol
Hypothalamic-pituitary-adrenal axis
Hypothalamo-Hypophyseal System
Hypothalamus
Immune response
Immune system
Immunity, Humoral
Lymphocytes
Neurons
Pituitary
Pituitary-Adrenal System
Spleen
Transplants & implants
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Summary:The hypothalamic-pituitary-adrenal axis modulates immunity in response to stress. In a recent report in the May 14, 2020 issue of Nature, Zhang et al. use optogenetic tools to investigate whether the splenic immune response is directly controlled by descending neuronal circuits activated in response to stress. The hypothalamic-pituitary-adrenal axis modulates immunity in response to stress. In a recent report in the May 14, 2020 issue of Nature, Zhang et al. use optogenetic tools to investigate whether the splenic immune response is directly controlled by descending neuronal circuits activated in response to stress.
ISSN:1074-7613
1097-4180
DOI:10.1016/j.immuni.2020.05.011