Does metabolomic profile differ with regard to birth weight?

Background Macrosomia and child obesity are growing health-care issues worldwide. The purpose of the study was to evaluate how extremely high or low birth weight affects metabolic markers evaluated in newborn screening. Methods The study was register-based and included full-term singletons born in I...

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Bibliographic Details
Published in:Pediatric research 2021-04, Vol.89 (5), p.1144-1151
Main Authors: Vidarsdottir, Harpa, Thorkelsson, Thordur, Halldorsson, Thorhallur Ingi, Bjarnason, Ragnar, Geirsson, Reynir Tomas, Rinaldo, Piero, Franzson, Leifur
Format: Article
Language:English
Subjects:
Basic Science Article
Birth Weight
Carnitine - analogs & derivatives
Carnitine - metabolism
Female
Gestational age
Humans
Iceland
Infant, Newborn
Male
Medical screening
Medicine
Medicine & Public Health
Metabolomics
Neonatal Screening
Newborn babies
Pediatric Surgery
Pediatrics
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Summary:Background Macrosomia and child obesity are growing health-care issues worldwide. The purpose of the study was to evaluate how extremely high or low birth weight affects metabolic markers evaluated in newborn screening. Methods The study was register-based and included full-term singletons born in Iceland from 2009 to 2012 with newborn screening samples taken 72–96 h after birth. Three groups based on birth weight were compared: low birth weight (
ISSN:0031-3998
1530-0447
DOI:10.1038/s41390-020-1033-0