Long term remission after ileorectal anastomosis in Crohn's colitis

Crohn's disease represents a heterogeneous entity, but its location tends to be relatively stable overtime. For extensive refractory Crohn's colitis, ileorectal anastomosis after colectomy is an engaging option, since the necessity of a permanent ileostomy is avoided. In our study, the lon...

Full description

Saved in:
Bibliographic Details
Published in:Digestive and liver disease 2021-05, Vol.53 (5), p.592-597
Main Authors: Salice, Marco, Rizzello, Fernando, Sgambato, Dolores, Calabrese, Carlo, Manguso, Francesco, Laureti, Silvio, Rottoli, Matteo, Poggioli, Gilberto, Gionchetti, Paolo
Format: Article
Language:English
Subjects:
Adult
Anastomosis, Surgical
Clinical trials
Colectomy - adverse effects
Colectomy - methods
Crohn Disease - surgery
Crohn's disease
Female
Humans
IBD
Ileorectal anastomosis
Ileostomy - adverse effects
Ileostomy - methods
Male
Middle Aged
Recurrence
Retrospective Studies
Surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Crohn's disease represents a heterogeneous entity, but its location tends to be relatively stable overtime. For extensive refractory Crohn's colitis, ileorectal anastomosis after colectomy is an engaging option, since the necessity of a permanent ileostomy is avoided. In our study, the long-term outcome of two groups of patients with Crohn's colitis who underwent colectomy and ileorectal anastomosis was compared. The first group had isolated colonic Crohn's disease without rectal involvement and perianal disease, while the second group included patients who had rectal and/or ileal involvement, with or without perianal disease. Between 1996 and 2016, in a single IBD tertiary center, 80 patients with a history of colectomy and ileorectal anastomosis for refractory Crohn's colitis were retrospectively identified. Recurrence of disease was diagnosed in 57/64 of patients with Crohn's colitis with rectal and/or ileal and/or perianal involvement compared with 1/16 of patients with isolated Crohn's colitis without rectal and perianal disease in a median time of recurrence of 2 years (IQR 1–6 years, minimum to maximum, 1–18 years, p 
ISSN:1590-8658
1878-3562
DOI:10.1016/j.dld.2020.06.021