The relationship between the presence of HPV infection and biofilm formation in cervicovaginal smears

Purpose To demonstrate and understand the association of HPV infection and biofilm formation. Methods The study consisted of cervicovaginal samples of 72 women who were evaluated at the colposcopy unit. Papanicolaou staining was used for cytological examination while “Crystal Violet Binding” assay w...

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Bibliographic Details
Published in:Infection 2020-10, Vol.48 (5), p.735-740
Main Authors: Donmez, Hanife Guler, Sahal, Gulcan, Akgor, Utku, Cagan, Murat, Ozgul, Nejat, Beksac, Mehmet Sinan
Format: Article
Language:English
Subjects:
Adult
Biofilms
Cervix Uteri - virology
Family Medicine
Female
General Practice
Humans
Infectious Diseases
Internal Medicine
Medicine
Medicine & Public Health
Middle Aged
Original Paper
Papillomaviridae - physiology
Papillomavirus Infections - physiopathology
Turkey
Vagina - virology
Vaginal Smears
Young Adult
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Summary:Purpose To demonstrate and understand the association of HPV infection and biofilm formation. Methods The study consisted of cervicovaginal samples of 72 women who were evaluated at the colposcopy unit. Papanicolaou staining was used for cytological examination while “Crystal Violet Binding” assay was performed to detect biofilm formation. Results HPV-DNA was positive in 55.5% ( n  = 40) of the patients. The biofilm formation rate was statistically significantly higher in the HPV-positive women (45%) compared to HPV-negative women (21.9%) ( P  
ISSN:0300-8126
1439-0973
DOI:10.1007/s15010-020-01478-5