An antiviral response beyond immune cells

Fibroblast, epithelial and endothelial cells are more than just the scaffold of an organ — it emerges that they communicate with immune cells and are primed to launch organ-specific gene-expression programs for antiviral defence. Fibroblast, epithelial and endothelial cells aid organ-specific defenc...

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Bibliographic Details
Published in:Nature (London) 2020-07, Vol.583 (7815), p.206-207
Main Authors: Gomes, Tomás, Teichmann, Sarah A.
Format: Article
Language:English
Subjects:
631/250
631/326/596
Activation-induced cytidine deaminase
Adaptive Immunity
Antiviral drugs
Cancer
Chromatin
Cytokines
Defense
Defense programs
Deoxyribonucleic acid
DNA
Fibroblasts
Gene expression
Gene sequencing
Genomes
Immune response
Immune system
Infections
Medical research
News And Views
Nucleotide sequence
Proteins
Ribonucleic acid
RNA
Spleen
Transcriptomics
Viral infections
Virus Diseases
Viruses
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Description
Summary:Fibroblast, epithelial and endothelial cells are more than just the scaffold of an organ — it emerges that they communicate with immune cells and are primed to launch organ-specific gene-expression programs for antiviral defence. Fibroblast, epithelial and endothelial cells aid organ-specific defence.
ISSN:0028-0836
1476-4687
DOI:10.1038/d41586-020-01916-2