Evaluation of Cost, Workflow, and Safety of Implementing a Vial Transfer Device for Ready-to-Mix Drugs at an Academic Medical Center

• Published in: Journal of pharmacy practice 2021-12, Vol.34 (6), p.908-912
• Main Authors: Tran, Lena K., Anger, Kevin E., Dell’Orfano, Heather, Rocchio, Megan A., Szumita, Paul M.
• Format: Article
• Language: English
• Subjects: Academic Medical Centers; Drug Compounding; Humans; Pharmaceutical Preparations; Prospective Studies; Retrospective Studies; Workflow
• ISSN: 0897-1900; 1531-1937
• DOI: 10.1177/0897190020938195

Objective: To evaluate the cost, workflow, and safety of implementing a vial transfer device system. Methods: In this retrospective analysis, pharmacy systems and electronic health record reports identified high-volume and high-cost medications prepared by a Vial2Bag® (V2B) system from July 2017 to June 2018. The major outcome was the extrapolated yearly cost avoidance (EYCA) from utilization of a V2B system, calculated by subtracting total costs of the V2B system from total cost of ready-to-use products and locally compounded sterile products. Secondary outcomes included a workflow and safety analysis. Results: Implementing a V2B system led to a total EYCA of $2 295 261. A total of 283 209 potential V2B units were available for dispensing from automated dispensing systems and 41 082 yearly sterile product room units were avoided. A 0.02% safety report incidence per V2B administration was calculated at our institution. Conclusion: Use of a V2B system resulted in a substantial cost avoidance compared to purchasing commercial products and preparing locally compounded sterile products. The V2B system appears to be a safe addition to further optimize workflow but may require further investigation in prospective analyses.