Effect of Rat Exposure to Moderate Pressure Oxygen Atmosphere on Resistance of Erythrocytes against Hemolysis

Exposure of male Wistar rats to oxygen atmosphere at moderate pressure (1.10-1.15 atm) for 4 h resulted in significant, transient, and reversible decrease in hemolytic resistance of peripheral blood erythrocytes. In 2 days after oxygen exposure, the bone marrow released young erythrocytes with enhan...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2020-06, Vol.169 (2), p.201-204
Main Authors: Izmest’eva, O. S., Dzikovskaya, L. A., Zhavoronkov, L. P.
Format: Article
Language:English
Subjects:
Biomedical and Life Sciences
Biomedicine
Cell Biology
Internal Medicine
Laboratory Medicine
Pathology
Proteins
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Summary:Exposure of male Wistar rats to oxygen atmosphere at moderate pressure (1.10-1.15 atm) for 4 h resulted in significant, transient, and reversible decrease in hemolytic resistance of peripheral blood erythrocytes. In 2 days after oxygen exposure, the bone marrow released young erythrocytes with enhanced hemolytic resistance as a compensation for oxygen injury. These findings suggest that normobaric oxygen load can be viewed as a stress factor of moderate intensity.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-020-04850-5