ILIB (intravascular laser irradiation of blood) as an adjuvant therapy in the treatment of patients with chronic systemic diseases—an integrative literature review

To perform an integrative review of the literature on the effectiveness of intravascular laser irradiation of blood (ILIB) as an adjunct therapy in the treatment of chronic systemic diseases. This is an integrative literature review that included non-randomized and randomized controlled clinical tri...

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Bibliographic Details
Published in:Lasers in medical science 2020-12, Vol.35 (9), p.1899-1907
Main Authors: Tomé, Ruan Felipe Ferreira, Silva, Diego Filipe Bezerra, dos Santos, Carlus Alberto Oliveira, de Vasconcelos Neves, Gabriella, Rolim, Ana Karina Almeida, de Castro Gomes, Daliana Queiroga
Format: Article
Language:English
Subjects:
Access routes
Adjuvant therapy
Blood
Boolean algebra
Clinical trials
Coronary artery
Dentistry
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diseases
Health services
Irradiation
Lasers
Literature reviews
Medical treatment
Medicine
Medicine & Public Health
Optical Devices
Optics
Patients
Photonics
Quantum Optics
Review Article
System effectiveness
Systemic diseases
Therapy
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Summary:To perform an integrative review of the literature on the effectiveness of intravascular laser irradiation of blood (ILIB) as an adjunct therapy in the treatment of chronic systemic diseases. This is an integrative literature review that included non-randomized and randomized controlled clinical trials that specifically evaluated the therapeutic effect of ILIB on chronic systemic diseases, without restriction of time, and written in English. The Medical Publications (PubMed)/MEDLINE database was used. MeSH (Medical Subject Headings) was used to select search descriptors with the Boolean operators “AND/OR.” After applying the inclusion and exclusion criteria, 13 articles were selected. Coronary diseases were the most prevalent, followed by type 2 diabetes mellitus, with the coronary artery being the most widely used access route for ILIB application. Despite the varied parameters and protocols for using this kind of therapy, all studies have shown satisfactory results in the patients’ clinical condition. ILIB proved to be effective in all organic systems, showing some positive result. However, studies on the effect of this therapy on various diseases are still scarce in the literature, and there is a need for more well-designed clinical trials to better understand the role of ILIB in various systemic diseases.
ISSN:0268-8921
1435-604X
DOI:10.1007/s10103-020-03100-4