Phytochemical Characterization and Effects on Cell Proliferation of Lentisk (Pistacia lentiscus) Berry Oil: a Revalued Source of Phenolics

The ethno-pharmaceutical use of the edible fixed oil produced from lentisk ( Pistacia lentiscus ) berries covers a long tradition in several Mediterranean regions. Many of the health-promoting properties of lentisk berry oil (LBO) have been associated with the content of polar (poly)phenolic compoun...

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Bibliographic Details
Published in:Plant foods for human nutrition (Dordrecht) 2020-12, Vol.75 (4), p.487-494
Main Authors: Siano, Francesco, Cutignano, Adele, Moccia, Stefania, Russo, Gian Luigi, Volpe, Maria Grazia, Picariello, Gianluca
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Ecology
Food Science
Nutrition
Original Paper
Plant Physiology
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Summary:The ethno-pharmaceutical use of the edible fixed oil produced from lentisk ( Pistacia lentiscus ) berries covers a long tradition in several Mediterranean regions. Many of the health-promoting properties of lentisk berry oil (LBO) have been associated with the content of polar (poly)phenolic compounds. However, the polar fraction (methanol 80%, v/v) of LBO (LBO-pf) remains poorly and inadequately characterized. We assessed the phytochemical composition (fatty acids, phytosterols and polyphenols) of cold-pressed LBO produced in Cilento (Campania region, Italy) over four years of production (2015–2018). Main phenolic compounds present in LBO-pf were identified and semi-quantified combining ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS) and HPLC with diode array detection. Phenolic compounds, also responsible for oil stability and antioxidant properties, are relatively abundant in LBO, compared to other edible oils. LBO-pf induced clear dose-dependent effects on the growth of HT-29 cell line derived from human colorectal adenocarcinoma, as evidenced by the cell cycle arrest. Our data support the health-promoting properties of cold-pressed LBO, which is obtained with good yield from spontaneous plants growing in semiarid regions.
ISSN:0921-9668
1573-9104
DOI:10.1007/s11130-020-00835-x