Comparison of invasive and non-invasive blood pressure measurements in anesthetized female Dorset cross-bred lambs (Ovis aries)

• Published in: Research in veterinary science 2020-10, Vol.132, p.257-261
• Main Authors: Izer, Jenelle, Wilson, Ronald
• Format: Article
• Language: English
• Subjects: Anesthesia; Anesthesia - veterinary; Animals; Arterial blood pressure; Blood pressure; Blood Pressure - physiology; Blood Pressure Determination - veterinary; Blood Pressure Monitors - veterinary; Catheters; Comparison; Data collection; Female; Femoral artery; Femur; Hematoma; Hypotension; Intubation; Isoflurane; Medical equipment; Monitoring; Noninvasive blood pressure; Oscillometry - veterinary; Pressure measurement; Sheep; Sheep - physiology; Veins & arteries; Ventilation; Veterinary medicine
• ISSN: 0034-5288; 1532-2661
• DOI: 10.1016/j.rvsc.2020.07.004

The purpose of this study was to determine the level of agreement between invasive and noninvasive blood pressure measurements in anesthetized, non-surgically manipulated Dorset cross-bred lambs. Twelve healthy female Dorset cross-bred lambs, weighing 37.3 ± 7.4 kg (mean ± SD) underwent isoflurane anesthesia for simultaneous measurement of systolic arterial pressure (SAP), mean arterial pressure (MAP) and diastolic arterial pressure (DAP) from an invasive blood pressure source and a noninvasive oscillometric source (O-NIBP). The femoral artery was catheterized for invasive blood pressure measurements, while noninvasive blood pressure was measured from a cuff placed on the antebrachium. The Bland-Altman method was used to calculate agreement between SAP, MAP and DAP measurements. The bias ± SD between SAP, MAP and DAP measurements was 3.6 ± 12.0, 4.9 ± 9.1 mmHg and 4.1 ± 8.0, respectively. The 95% limits of agreement for SAP, MAP and DAP were − 19.9 to 27.1, −13.0 to 22.8 mmHg, and − 11.7 to 19.9, respectively. Overall, agreement was poor between femoral IBP and O-NIBP monitoring techniques in anesthetized Dorset cross-bred lambs, with O-NIBP underestimating the femoral IBP. Arterial blood pressure should be most accurately measured using an invasive blood pressure monitoring technique in lambs undergoing isoflurane anesthesia. •Our research study is novel in that it is the first to compare invasive and non-invasive blood pressure measurements in non-surgically manipulated Dorset cross-bred lambs.•Poor agreement was present between NIBP and femoral arterial blood pressure measurements in isoflurane-anesthetized Dorset cross-bred lambs.•Our study is also novel in that it is the first to be published comparing central (femoral) arterial blood pressure measurement to non-invasive blood pressure measurement in lambs.