Glucose-Lipid Metabolism in Obesity with Elevated Prolactin Levels and Alteration of Prolactin Levels After Laparoscopic Sleeve Gastrectomy

Purpose We investigated the differences in metabolism between obesity with or without increased prolactin (PRL) and the change in PRL after laparoscopic sleeve gastrectomy (LSG). Methods Patients were divided into two groups: obesity with normal PRL (NP, n  = 123) and high PRL (HP, n  = 108). Glucos...

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Bibliographic Details
Published in:Obesity surgery 2020-10, Vol.30 (10), p.4004-4013
Main Authors: Wang, Xingchun, Ma, Bingwei, Li, Guifang, Sheng, Chunjun, Yang, Peng, Gao, Jingyang, Qu, Shen
Format: Article
Language:English
Subjects:
Cross-Sectional Studies
Female
Gastrectomy
Glucose
Humans
Laparoscopy
Lipid Metabolism
Lipids
Male
Medicine
Medicine & Public Health
Metabolism
Obesity
Obesity - surgery
Obesity, Morbid - surgery
Original Contributions
Prolactin
Surgery
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Summary:Purpose We investigated the differences in metabolism between obesity with or without increased prolactin (PRL) and the change in PRL after laparoscopic sleeve gastrectomy (LSG). Methods Patients were divided into two groups: obesity with normal PRL (NP, n  = 123) and high PRL (HP, n  = 108). Glucose-lipid metabolism and inflammation were measured. A total of 115 patients with obesity (NP, n  = 64; HP, n  = 51) underwent LSG were recruited, and PRL was measured at 12 months after LSG. Results (1) Blood glucose (BG), total cholesterol (TCH), LDL, triglyceride, and TNF-α were lower in the HP than in the NP group in the cross-sectional study (all P  
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-020-04771-2