Radiographic Splenic Artery Involvement Is a Poor Prognostic Factor in Upfront Surgery for Patients with Resectable Pancreatic Body and Tail Cancer

Purpose The prognostic impact of radiographic splenic vessel involvement in pancreatic cancer remains unclear. We evaluate its oncological significance in resectable pancreatic body/tail cancer. Patients and Methods We retrospectively review 102 cases of resectable pancreatic cancer and 51 of border...

Full description

Saved in:
Bibliographic Details
Published in:Annals of surgical oncology 2021-03, Vol.28 (3), p.1521-1532
Main Authors: Kawai, Manabu, Hirono, Seiko, Okada, Ken-ichi, Miyazawa, Motoki, Kitahata, Yuji, Kobayashi, Ryohei, Ueno, Masaki, Hayami, Shinya, Yamaue, Hiroki
Format: Article
Language:English
Subjects:
Carcinoma, Pancreatic Ductal - surgery
Cytology
Humans
Medical prognosis
Medicine
Medicine & Public Health
Neoadjuvant Therapy
Oncology
Pancreatectomy
Pancreatic cancer
Pancreatic Neoplasms - diagnostic imaging
Pancreatic Neoplasms - surgery
Pancreatic Tumors
Patients
Prognosis
Retrospective Studies
Spleen
Splenic artery
Splenic Artery - diagnostic imaging
Splenic Artery - surgery
Surgery
Surgical Oncology
Survival
Survival Rate
Tails
Veins & arteries
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose The prognostic impact of radiographic splenic vessel involvement in pancreatic cancer remains unclear. We evaluate its oncological significance in resectable pancreatic body/tail cancer. Patients and Methods We retrospectively review 102 cases of resectable pancreatic cancer and 51 of borderline resectable pancreatic cancer (BRPC) who underwent pancreatectomy for pancreatic body/tail cancer. Resectable pancreatic body/tail cancer was classified into one of three categories based on radiographic splenic vessel involvement. Results Among 102 cases of resectable pancreatic cancer, 37 (36.3%), 35 (34.3%), and 30 cases (29.4%) were classified as no splenic vessel involvement (R none ), splenic vein involvement (RV), and splenic artery involvement (RA), respectively. Disease-free survival (DFS) among patients with R none , RV, RA, and BRPC was 58.5, 18.4, 10.8, and 9.2 months, respectively. Patients with RV and RA had significantly poorer DFS than patients with R none ( P  = 0.010, P  
ISSN:1068-9265
1534-4681
DOI:10.1245/s10434-020-08922-8