Orientia tsutsugamushi

Orientia tsutsugamushi is an obligate intracellular bacterial pathogen that causes the mite-borne human disease scrub typhus, one of the most widespread and severe rickettsial infections. Symptoms typically begin 7–14 days after inoculation and include headache, fever, rash, myalgia, and a painless...

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Bibliographic Details
Published in:Trends in microbiology (Regular ed.) 2020-09, Vol.28 (9), p.780-781
Main Authors: Wongsantichon, Jantana, Jaiyen, Yanin, Dittrich, Sabine, Salje, Jeanne
Format: Article
Language:English
Subjects:
Disease control
Fever
Headache
Inoculation
Microbiology
Mites
Myalgia
obligate intracellular bacteria
Orientia tsutsugamushi
reductive evolution
rickettsia
Scrub typhus
Signs and symptoms
vector-borne diseases
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Summary:Orientia tsutsugamushi is an obligate intracellular bacterial pathogen that causes the mite-borne human disease scrub typhus, one of the most widespread and severe rickettsial infections. Symptoms typically begin 7–14 days after inoculation and include headache, fever, rash, myalgia, and a painless eschar at the site of the mite’s bite. Untreated, the disease can escalate to cause multiple organ failure and death. Major challenges to disease control include slow and inaccurate diagnostic tests and low awareness amongst clinicians.
ISSN:0966-842X
1878-4380
DOI:10.1016/j.tim.2020.02.014