Official recommendations for vitamin D through the life stages in developed countries

Inadequate vitamin D nutritional status is prevalent worldwide and has been associated with autoimmune disorders, heart disease, deadly cancers, insulin resistance, inflammation, neurological disorders, adverse outcomes in pregnancy, and increased risk for mortality. Expert recommendations for vitam...

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Bibliographic Details
Published in:European journal of clinical nutrition 2020-11, Vol.74 (11), p.1514-1518
Main Authors: Kimball, Samantha M., Holick, Michael F.
Format: Article
Language:English
Subjects:
25-Hydroxyvitamin D
692/163/2743
692/700/2814
Alfacalcidol
Autoimmune diseases
Calcifediol
Calciferol
Cancer
Cardiovascular diseases
Clinical Nutrition
Coronary artery disease
Developed countries
Disease resistance
Epidemiology
Health aspects
Health policy
Health promotion
Heart diseases
Industrial nations
Insulin
Internal Medicine
Medicine
Medicine & Public Health
Metabolic Diseases
Mortality risk
Neurological diseases
Nutrient deficiency
Nutrition
Nutritional status
Public Health
Recommended daily allowances
Review Article
Risk management
Risk reduction
Vitamin D
Vitamin deficiency
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Summary:Inadequate vitamin D nutritional status is prevalent worldwide and has been associated with autoimmune disorders, heart disease, deadly cancers, insulin resistance, inflammation, neurological disorders, adverse outcomes in pregnancy, and increased risk for mortality. Expert recommendations for vitamin D intake differ between governmental agencies and practice guidelines from medical societies due to differences in the definition of vitamin D deficiency, insufficiency and sufficiency based on serum 25-hydroxyvitamin D [25(OH)D] concentrations. In addition, separate health promotion bodies also provide targeted recommendations for the prevention of specific disorders such as reducing risk for developing some cancers and autoimmune diseases. We review and provide perspectives regarding various recommendations from the Institute of Medicine (IOM, United States) and Health Canada, the European Food Safety Authority (EFSA), the Scientific Advisory Committee on Nutrition (SACN; United Kingdom), the World Health Organization, the Endocrine Society and other expert groups by life stage as a guide intended for clinician use.
ISSN:0954-3007
1476-5640
DOI:10.1038/s41430-020-00706-3