Children and adolescents cancer incidence, mortality and survival a population-based study in Midwest of Brazil

• Published in: Cancer epidemiology 2020-10, Vol.68, p.101795-101795, Article 101795
• Main Authors: de Oliveira, Max Moura, e Silva, Diego Rodrigues Mendonça, Ramos, Fabrícia Rezende, Curado, Maria Paula
• Format: Article
• Language: English
• Subjects: Adolescent; Adolescents; Age; Age groups; Brazil - epidemiology; Cancer; Child; Child mortality; Child, Preschool; Childhood cancer; Children; Epidemiology; Estimates; Female; Humans; Incidence; Infant; Infant, Newborn; Information systems; Leukemia; Lymphoma; Male; Mortality; Mortality - trends; Neoplasms - epidemiology; Neoplasms - mortality; Pediatrics; Population; Population studies; Population-based studies; Prognosis; Relative survival; Survival; Survival Rate; Teenagers; Trends; Tumors
• ISSN: 1877-7821; 1877-783X
• DOI: 10.1016/j.canep.2020.101795

•The most common cancer in children and adolescents of Goiania are leukemias.•The incidence and mortality rates of children and adolescents cancers in Goiania were higher.•The 5-years relative survival of cancer in Goiania was 62.4 % (1996–2012).•There were an improvement in relative survival in the most recent period. To identify time trends in incidence, mortality and 5-year relative survival in children and adolescents with cancer in Goiania-Goias, Brazil, during the years of 1996–2012. Incidence and mortality age-standardized rates (ASR) were calculated, and trends were identified by determining the Average Annual Percentage Change (AAPC). Five-year relative survival were estimated. The overall incidence ASR (1996–2012) was 164.2/1,000,000 in both genders. In boys was 176.6/1,000,000, in girls it was 151.8/1,000,000. Overall mortality ASR for both gender were 69.3/1,000,000. Incidence rates (AAPC: -0.5; 95 %CI: -2.4;1.4) and mortality rates (AAPC: 0.0; 95 %CI: -2.6;2;7) were stable in the period. Five-year relative survival for all cancers were 63.9 %, with the highest survival rates for retinobastoma (83.5 %), germ cell tumors (79.8 %), and lymphomas (72.7 %). It was observed an increase in survival in the period from de 62.8 % (1996 a 2003) to 65.0 % from 2004 to 2012. Children and adolescent cancer incidence and mortality rates were higher in Goiania, but both are stable overall. The relative survival slighly improved in the period but remained lower mainly for leukemias.