Patterns of nightly CPAP usage in OSA patients with suboptimal treatment adherence

Low adherence impairs the effectiveness of continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnoea (OSA), but knowledge on CPAP usage micro-patterns is mostly lacking. Thus, the aim of this study was to analyse usage micro-patterns among patients with suboptimal...

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Published in:Sleep medicine 2020-10, Vol.74, p.109-115
Main Authors: Grewe, Fabian A., Bradicich, Matteo, Gaisl, Thomas, Roeder, Maurice, Thiel, Sira, Sievi, Noriane A., Kohler, Malcolm
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Language:English
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Adherence
Continuous positive airway pressure
Obstructive sleep apnoea
Usage-patterns
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creator Grewe, Fabian A.
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description Low adherence impairs the effectiveness of continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnoea (OSA), but knowledge on CPAP usage micro-patterns is mostly lacking. Thus, the aim of this study was to analyse usage micro-patterns among patients with suboptimal CPAP adherence. We analysed CPAP usage datasets comprising the initial 31 nights of therapy. By employing a threshold of 4 h usage in at least 70% of nights, we subdivided the patients into suboptimal and optimal users. We investigated single CPAP start- and stop-points, and introduced the parameter “interruption-rate”, by dividing the amount of therapy interruptions per night by the usage duration per night. This parameter represents the amount of interruptions per 1 h of CPAP usage. Group comparison analysis was performed via t-test, Wilcoxon rank sum-test, and via Chi2-test. We included datasets of 48 suboptimal and 48 optimal users (55.9 ± 11.3 years, 83.3% men) in the analysis. Interruption-rate was significantly higher among suboptimal users, when compared with optimal users (median (quartiles) 0.24 (0.14/0.45) versus 0.15 (0.05/0.28), p 
doi_str_mv 10.1016/j.sleep.2020.05.042
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subjects Adherence
Continuous positive airway pressure
Obstructive sleep apnoea
Usage-patterns
title Patterns of nightly CPAP usage in OSA patients with suboptimal treatment adherence
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