Health‐related quality of life after pediatric heart transplantation in early childhood

Background There is limited information about HRQL after pediatric heart transplantation at a young age. Methods Prospective follow‐up study of children who received a heart transplant at age ≤4 years. HRQL was assessed using the PedsQLTM 4.0 at age 4.5 years. This cohort was compared with healthy c...

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Bibliographic Details
Published in:Pediatric transplantation 2020-11, Vol.24 (7), p.e13822-n/a
Main Authors: Garcia Guerra, Gonzalo, Bond, Gwen Y., Joffe, Ari R., Dinu, Irina A, Hajihosseini, Morteza, Al‐Aklabi, Mohammed, Robertson, Charlene M. T., Urschel, Simon
Format: Article
Language:English
Subjects:
Age
Childhood
Children
Chronic illnesses
Creatinine
heart transplant
Heart transplantation
Heart transplants
Lactic acid
outcome
pediatric transplantation
Pediatrics
Quality of life
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Summary:Background There is limited information about HRQL after pediatric heart transplantation at a young age. Methods Prospective follow‐up study of children who received a heart transplant at age ≤4 years. HRQL was assessed using the PedsQLTM 4.0 at age 4.5 years. This cohort was compared with healthy children, children with CHD, and with chronic conditions. Peri‐operative factors associated with HRQL were also explored. Results Of 66 eligible patients, 15 (23%) died prior to the HRQL assessment and 2 (3%) were lost to follow‐up, leaving 49 patients. Indication for transplantation was CHD in 27 (55%) and CMP in 22 (45%). Median age (IQR) at transplant was 9 (5‐31) months. HRQL was significantly lower in transplanted children compared to population norms (65.3 vs 87.3, P 
ISSN:1397-3142
1399-3046
DOI:10.1111/petr.13822