Outcomes of retrograde chronic total occlusion percutaneous coronary intervention: A report from the OPEN‐CTO registry

Objectives We sought to assess in‐hospital and long‐term outcomes of retrograde compared with antegrade‐only percutaneous coronary intervention for chronic total occlusion (CTO PCI). Background Procedural and clinical outcomes following retrograde compared with antegrade‐only CTO PCI remain unknown....

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Bibliographic Details
Published in:Catheterization and cardiovascular interventions 2021-05, Vol.97 (6), p.1162-1173
Main Authors: Kalra, Sanjog, Doshi, Darshan, Sapontis, James, Kosmidou, Ioanna, Kirtane, Ajay J., Moses, Jeffrey W., Riley, Robert F., Jones, Philip, Nicholson, William J., Salisbury, Adam C., Lombardi, William L., McCabe, James M., Pershad, Ashish, Hirai, Taishi, Hakemi, Emad, Russo, Juan J., Prasad, Megha, Ahmad, Yousif, Hatem, Raja, Gkargkoulas, Fotis, Spertus, John A., Wyman, R. Michael, Jaffer, Farouc, Spaedy, Anthony, Cook, Stephen, Marso, Steven P., Nugent, Karen, Federici, Robert, Yeh, Robert W., Leon, Martin B., Stone, Gregg W., Ali, Ziad A., Parikh, Manish A., Maehara, Akiko, Cohen, David J., Batres, Candido, Grantham, J. Aaron, Karmpaliotis, Dimitri
Format: Article
Language:English
Subjects:
Angina
Angioplasty
Cerebral infarction
chronic total occlusion
Death
Heart
Heart surgery
Myocardial infarction
Occlusion
OPEN‐CTO
percutaneous coronary intervention
Quality of life
retrograde
Sensitivity analysis
Stroke
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Summary:Objectives We sought to assess in‐hospital and long‐term outcomes of retrograde compared with antegrade‐only percutaneous coronary intervention for chronic total occlusion (CTO PCI). Background Procedural and clinical outcomes following retrograde compared with antegrade‐only CTO PCI remain unknown. Methods Using the core‐lab adjudicated OPEN‐CTO registry, we compared the outcomes of retrograde to antegrade‐only CTO PCI. Primary endpoints included were in‐hospital major adverse cardiac and cerebrovascular events (MACCE) (all‐cause death, stroke, myocardial infarction [MI], emergency cardiac surgery, or clinically significant perforation) and MACCE at 1‐year (all‐cause death, MI, stroke, target lesion revascularization, or target vessel reocclusion). Results Among 885 single CTO procedures from the OPEN‐CTO registry, 454 were retrograde and 431 were antegrade‐only. Lesion complexity was higher (J‐CTO score: 2.7 vs. 1.9; p 
ISSN:1522-1946
1522-726X
DOI:10.1002/ccd.29230