Early recurrence after pulmonary vein isolation is associated with inferior long‐term outcomes: Insights from a retrospective cohort study

Aims The aim of this retrospective cohort study was to assess the influence of early recurrence (ER) after pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation (AF) on long‐term outcomes and to identify clinical variables associated with ER. Methods We retrospectively collected clinical...

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Published in:Pacing and clinical electrophysiology 2020-10, Vol.43 (10), p.1156-1164
Main Authors: Kalinsek, Tine Prolic, Kottmaier, Marc, Telishevska, Marta, Berger, Florian, Semmler, Verena, Popa, Miruna, Brkic, Amir, Lengauer, Sarah, Otgonbayar, Ulamnemekh, Koch‐Büttner, Katharina, Bartowiak, Marcin, Kornmayer, Marielouise, Brooks, Stephanie, Risse, Elena, Kathan, Susanne, Hofmann, Monika, Grebmer, Christian, Reents, Tilko, Hessling, Gabriele, Deisenhofer, Isabel, Bourier, Felix
Format: Article
Language:English
Subjects:
atrial fibrillation
blanking period
Cardiac arrhythmia
catheter ablation
Clinical trials
Cohort analysis
Diabetes mellitus
early recurrence
Fibrillation
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Summary:Aims The aim of this retrospective cohort study was to assess the influence of early recurrence (ER) after pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation (AF) on long‐term outcomes and to identify clinical variables associated with ER. Methods We retrospectively collected clinical and procedural data from 1285 patients with paroxysmal AF who underwent PVI from 2011 to 2016. Kaplan‐Meier, receiver operating characteristic (ROC) curve, logistic and Cox regression analyses were performed to analyze the influence of ER on long‐term outcomes. Results ER was observed in 13% of patients. Kaplan‐Meier analyses showed significantly different outcomes in 1285 patients with and without ER (49% vs 74%, log rank P 
ISSN:0147-8389
1540-8159
DOI:10.1111/pace.14060