Prenatal diagnosis of single umbilical artery and postpartum outcome

• Published in: European journal of obstetrics & gynecology and reproductive biology 2020-11, Vol.254, p.6-10
• Main Authors: Li, Tian-gang, Wang, Gang, Xie, Fang, Yao, Juan-min, Yang, Lan, Wang, Meng-lin, Wang, Jian, Xing, Lin, Nie, Fang
• Format: Article
• Language: English
• Subjects: Child; Chromosome abnormalities; Female; Fetus; Humans; Infant, Newborn; Isolated single umbilical artery; Postpartum outcome; Postpartum Period; Pregnancy; Prenatal Diagnosis; Retrospective Studies; Single umbilical artery; Single Umbilical Artery - diagnostic imaging; Single Umbilical Artery - epidemiology; Ultrasonography, Prenatal; Umbilical Arteries - diagnostic imaging
• ISSN: 0301-2115; 1872-7654
• DOI: 10.1016/j.ejogrb.2020.08.047

To investigate the incidence of the single umbilical artery (SUA) malformation and postpartum outcomes in a retrospective analysis of 781 fetuses. This retrospective analysis included 781 pregnant women carrying singleton fetuses diagnosed with SUA at Gansu Provincial Maternal and Child-care Hospital between 2013 and 2019. Detailed data on maternal and fetal characteristics and postpartum outcomes were obtained. In total, 624 (79.9 %) fetuses were diagnosed with isolated SUA and 157 (20.1 %) fetuses had SUA together with other structural and/or chromosome abnormalities. The highest incidence of malformation was found in the urinary system, followed by the cardiovascular system and digestive system. The incidence of SUA was 59.1 % on the right side and 40.9 % on the left side. Fetuses with SUA and other abnormalities tended to have a lower mean birth weight (3061 g vs 3201 g, p