Distribution and Progression of Inflammatory Chorioretinal Lesions Related to Multifocal Choroiditis and Their Correlations with Clinical Outcomes at 24 Months

To analyze distribution and progression of multifocal choroiditis (MFC) inflammatory lesions and their correlations with clinical outcomes at 24 months. Distribution and progression of inflammatory lesions were evaluated in eyes with MFC using a semi-automatic approach based on fundus autofluorescen...

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Published in:Ocular immunology and inflammation 2022-02, Vol.30 (2), p.409-416
Main Authors: Erba, Stefano, Cozzi, Mariano, Xhepa, Alba, Cereda, Matteo, Staurenghi, Giovanni, Invernizzi, Alessandro
Format: Article
Language:English
Subjects:
Autofluorescence
Choroiditis - diagnosis
Choroiditis - pathology
Fluorescein Angiography - methods
Humans
inflammatory lesions
Multifocal Choroiditis
multimodal imaging
optical coherence tomography
punctate inner choroidopathy
Recurrence
Retrospective Studies
Tomography, Optical Coherence - methods
uveitis
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container_end_page 416
container_issue 2
container_start_page 409
container_title Ocular immunology and inflammation
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creator Erba, Stefano
Cozzi, Mariano
Xhepa, Alba
Cereda, Matteo
Staurenghi, Giovanni
Invernizzi, Alessandro
description To analyze distribution and progression of multifocal choroiditis (MFC) inflammatory lesions and their correlations with clinical outcomes at 24 months. Distribution and progression of inflammatory lesions were evaluated in eyes with MFC using a semi-automatic approach based on fundus autofluorescence. Twenty-four-months clinical outcomes were correlated with baseline features. Twenty-five eyes from 20 patients were enrolled. Visual acuity (VA) significantly improved from baseline to 24 months. Chorioretinal lesions spared the fovea in most eyes. The area of inflammatory lesions at 24 months significantly increased. Final number and area of lesions were significantly influenced by baseline features. Inflammatory lesions enlarged over time regardless of MFC recurrences. New lesion and MFC relapses did not affect final outcomes. Final VA correlated with baseline VA. Scars resulting from MFC lesions enlarged overtime even when the disease was under control. New lesions and MFC relapses did not affect final outcomes.
doi_str_mv 10.1080/09273948.2020.1800048
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Distribution and progression of inflammatory lesions were evaluated in eyes with MFC using a semi-automatic approach based on fundus autofluorescence. Twenty-four-months clinical outcomes were correlated with baseline features. Twenty-five eyes from 20 patients were enrolled. Visual acuity (VA) significantly improved from baseline to 24 months. Chorioretinal lesions spared the fovea in most eyes. The area of inflammatory lesions at 24 months significantly increased. Final number and area of lesions were significantly influenced by baseline features. Inflammatory lesions enlarged over time regardless of MFC recurrences. New lesion and MFC relapses did not affect final outcomes. Final VA correlated with baseline VA. Scars resulting from MFC lesions enlarged overtime even when the disease was under control. 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source Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list)
subjects Autofluorescence
Choroiditis - diagnosis
Choroiditis - pathology
Fluorescein Angiography - methods
Humans
inflammatory lesions
Multifocal Choroiditis
multimodal imaging
optical coherence tomography
punctate inner choroidopathy
Recurrence
Retrospective Studies
Tomography, Optical Coherence - methods
uveitis
title Distribution and Progression of Inflammatory Chorioretinal Lesions Related to Multifocal Choroiditis and Their Correlations with Clinical Outcomes at 24 Months
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