Feasibility analysis of external application of Xiao-Shuan-San in preventing PICC-related thrombosis

•PICC-related thrombosis is very common in clinic.•External application of Xiao-Shuan-San can reduce the incidence of PICC-related thrombosis and other complications.•External application of Xiao-Shuan-San can decrease the Vmax value of axillary vein. We aim to analyze the feasibility of external ap...

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Bibliographic Details
Published in:Complementary therapies in medicine 2020-08, Vol.52, p.102448-102448, Article 102448
Main Authors: Li, Jie-Ping, Jiang, Wen-Wen, Bi, Wei-Kang, Jiang, Cui-Hong, Li, Ze-Kun, Zou, Yong, Zhang, Shao-Bing, Bi, Ming-Jun, Li, Qin
Format: Article
Language:English
Subjects:
Administration, Topical
Anticoagulants
Blood clots
Blood flow
Catheterization
Catheterization, Peripheral - adverse effects
Catheters
Chemotherapy
Coagulation
Comorbidity
Complications
Drugs, Chinese Herbal - therapeutic use
External application
Feasibility Studies
Female
Flow velocity
Hospitals
Humans
Intubation
Male
Medical instruments
Middle Aged
Nosocomial infections
Pain
Phlebitis
PICC
Pulmonary embolisms
Thromboembolism
Thrombosis
Thrombosis - prevention & control
Ultrasonic imaging
Vein thrombosis
Veins
Veins & arteries
Xiao-Shuan-San
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Summary:•PICC-related thrombosis is very common in clinic.•External application of Xiao-Shuan-San can reduce the incidence of PICC-related thrombosis and other complications.•External application of Xiao-Shuan-San can decrease the Vmax value of axillary vein. We aim to analyze the feasibility of external application of Xiao-Shuan-Santo prevent peripherally inserted central catheter (PICC) -related thrombosis. A total of 218 patients with PICC catheterization were randomly divided into a control group (n = 103) and a treatment group (n = 115). Patients in the treatment group received additional external application of Xiao-Shuan-San. The changes of coagulation index, the incidence of PICC-related thrombosis and other complications, and the maximum blood flow rate (Vmax) of axillary vein were observed at 1 day before catheterization and 30 days after PICC. At 30 days after PICC, the incidence of PICC-related thrombosis and other adverse events in the treatment group were obviously lower than that in the control group (P 
ISSN:0965-2299
1873-6963
DOI:10.1016/j.ctim.2020.102448