Discrimination of well-differentiated liposarcoma from benign lipoma on sonography: an uncontrolled retrospective study

Purpose Well-differentiated liposarcoma, the most common subtype of liposarcoma, should be discriminated from benign lipoma. However, features on sonography for discriminating these two types of tumor have not been fully investigated. The present study was therefore aimed at clarifying differences i...

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Bibliographic Details
Published in:Journal of medical ultrasonics (2001) 2020-10, Vol.47 (4), p.617-623
Main Authors: Shimamori, Naoko, Kishino, Tomonori, Okabe, Naota, Morii, Takeshi, Matsushima, Satsuki, Yamasaki, Satoko, Ohtsuka, Kouki, Shibahara, Junji, Ohnishi, Hiroaki, Watanabe, Takashi
Format: Article
Language:English
Subjects:
Adult
Age Distribution
Aged
Buttocks - diagnostic imaging
Buttocks - pathology
Calcification
Chi-square test
Comparative analysis
Connective tissue tumors
Diagnosis, Differential
Female
Histopathology
Humans
Imaging
Lipoma - diagnostic imaging
Liposarcoma
Liposarcoma - diagnostic imaging
Liposarcoma - pathology
Male
Margins of Excision
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Middle Aged
Original Article–Orthopedics
Radiology
Retrospective Studies
Tumors
Ultrasonic imaging
Ultrasonography - methods
Ultrasound
Ultrasound imaging
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Summary:Purpose Well-differentiated liposarcoma, the most common subtype of liposarcoma, should be discriminated from benign lipoma. However, features on sonography for discriminating these two types of tumor have not been fully investigated. The present study was therefore aimed at clarifying differences in sonographic findings between well-differentiated liposarcoma and lipoma. Methods The study population comprised 23 cases of well-differentiated liposarcoma and 181 cases of lipoma. We investigated differences in sonographic appearance and pathological findings between the two types of tumor. Results Well-differentiated liposarcoma tended to develop more frequently in older patients and in the lower extremities including the gluteal region, compared with lipoma. Concerning sonographic findings, both tumors exhibited well-defined margins and heterogeneous internal echogenicity, including typical tiny striated hyperechoic lines. Well-differentiated liposarcoma was characterized by a higher frequency of the following findings compared with lipoma: (1) deep location, (2) irregular shape, (3) large diameter, (4) hyperechogenicity compared to surrounding tissue, and (5) presence of vascularity on Doppler sonography ( p  
ISSN:1346-4523
1613-2254
DOI:10.1007/s10396-020-01051-5