Symmetry in the making

After years of speculation on the origins of symmetry-making and -breaking during crystallization, time-resolved in situ scanning probe microscopy and all-atom molecular dynamics simulations have shown that the formation of olanzapine crystals largely occurs by the incorporation of centrosymmetric d...

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Bibliographic Details
Published in:Nature chemistry 2020-10, Vol.12 (10), p.887-888
Main Author: Reutzel-Edens, Susan M.
Format: Article
Language:English
Subjects:
639/638/298/923/966
639/638/542
Analytical Chemistry
Biochemistry
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Crystallization
Crystals
Dimers
Inorganic Chemistry
Molecular dynamics
News & Views
news-and-views
Olanzapine
Organic Chemistry
Physical Chemistry
Scanning probe microscopy
Solutions
Symmetry
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Summary:After years of speculation on the origins of symmetry-making and -breaking during crystallization, time-resolved in situ scanning probe microscopy and all-atom molecular dynamics simulations have shown that the formation of olanzapine crystals largely occurs by the incorporation of centrosymmetric dimers into growth sites.
ISSN:1755-4330
1755-4349
DOI:10.1038/s41557-020-0547-8