Treatment of women's sexual dysfunction using Apium graveolens L. Fruit (celery seed): A double-blind, randomized, placebo-controlled clinical trial

Traditional manuscripts refer to plants such as Apium graveolens L. Fruit (celery seed), which could be used to improve sexual function among women. Since that time, local herbal shops in Iran continue to provide this herb as a natural aphrodisiac product. This study aimed to evaluate the efficacy a...

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Bibliographic Details
Published in:Journal of ethnopharmacology 2021-01, Vol.264, p.113400-113400, Article 113400
Main Authors: Hessami, Kamran, Rahnavard, Tahereh, Hosseinkhani, Ayda, Azima, Sara, Sayadi, Mehrab, Faraji, Azam, Emamghoreishi, Massoumeh, Vafaei, Homeira, Hessami, Anahita, Foroughinia, Leila, Maasumeh kaviani, Roozmeh, Shohreh, Asadi, Nasrin
Format: Article
Language:English
Subjects:
Adolescent
Adult
Apium
Celery seed
Double-Blind Method
Female
Female sexual dysfunction
Fruit
FSFI questionnaire
Herbal medicine
Humans
Iran - ethnology
Plant Extracts - administration & dosage
Plant Extracts - isolation & purification
Seeds
Sexual Dysfunction, Physiological - diagnosis
Sexual Dysfunction, Physiological - diet therapy
Sexual Dysfunction, Physiological - ethnology
Treatment Outcome
Young Adult
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Summary:Traditional manuscripts refer to plants such as Apium graveolens L. Fruit (celery seed), which could be used to improve sexual function among women. Since that time, local herbal shops in Iran continue to provide this herb as a natural aphrodisiac product. This study aimed to evaluate the efficacy and safety of celery seed for the treatment of female sexual dysfunction. In this parallel, randomized, double-blinded clinical trial, 80 women were assigned to receive either 500 mg of celery seed or placebo 3 times a day for a period of 6 weeks (n = 40 per group). The female sexual function index (FSFI) questionnaire was used to evaluate women's sexual function before and after treatment. At the end of the sixth week, an improvement in the total FSFI score was significantly greater in celery seed-treated women than those receiving the placebo (P 
ISSN:0378-8741
1872-7573
DOI:10.1016/j.jep.2020.113400