Super-resolution imaging of bacterial pathogens and visualization of their secreted effectors

ABSTRACT Recent advances in super-resolution imaging techniques, together with new fluorescent probes have enhanced our understanding of bacterial pathogenesis and their interplay within the host. In this review, we provide an overview of what these techniques have taught us about the bacterial life...

Full description

Saved in:
Bibliographic Details
Published in:FEMS microbiology reviews 2021-03, Vol.45 (2)
Main Authors: Singh, Moirangthem Kiran, Kenney, Linda J
Format: Article
Language:English
Subjects:
Bacteria
Fluorescent indicators
Image resolution
Imaging techniques
Pathogenesis
Virulence
Virulence factors
Citations: Items that this one cites
Items that cite this one
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:ABSTRACT Recent advances in super-resolution imaging techniques, together with new fluorescent probes have enhanced our understanding of bacterial pathogenesis and their interplay within the host. In this review, we provide an overview of what these techniques have taught us about the bacterial lifestyle, the nucleoid organization, its complex protein secretion systems, as well as the secreted virulence factors. This review focuses on how recent advances in super-resolution imaging have been applied to studies of bacterial pathogens.
ISSN:1574-6976
0168-6445
1574-6976
DOI:10.1093/femsre/fuaa050