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Gap between UAS and ureteroscope predicts renal stone-free rate after flexible ureteroscopy with the fragmentation technique

Purpose To assess the effect of our new classification on surgical outcomes after flexible ureteroscopy (fURS) for kidney stones. Methods We retrospectively examined 128 patients after single renal fURS procedures performed using ureteral access sheaths (UASs) with the fragmentation technique. Based...

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Published in:World journal of urology 2021-07, Vol.39 (7), p.2733-2739
Main Authors: Komeya, Mitsuru, Odaka, Hisakazu, Watanabe, Takahiko, Kiuchi, Hirokazu, Ogawa, Takehiko, Yao, Masahiro, Matsuzaki, Junichi
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container_title World journal of urology
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Odaka, Hisakazu
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description Purpose To assess the effect of our new classification on surgical outcomes after flexible ureteroscopy (fURS) for kidney stones. Methods We retrospectively examined 128 patients after single renal fURS procedures performed using ureteral access sheaths (UASs) with the fragmentation technique. Based on the gap (calculated by subtracting the ureteroscope diameter from the UAS diameter), enrolled patients were divided into three groups: small (
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Methods We retrospectively examined 128 patients after single renal fURS procedures performed using ureteral access sheaths (UASs) with the fragmentation technique. Based on the gap (calculated by subtracting the ureteroscope diameter from the UAS diameter), enrolled patients were divided into three groups: small (&lt; 0.6 mm), medium (0.6 to &lt; 1.2 mm), and large space groups (≥ 1.2 mm). Stone-free (SF) status was defined as either complete absence of stones (SF) or the presence of stones &lt; 4 mm in diameter on non-contrast computed tomography (NCCT). Results The SF rate was significantly lower in the small space group (50% in small, 97.9% in medium, 89.2% in large; p  = 0.001). Perioperative complications over Clavien–Dindo Grade I were observed in 16.7%, 4.2%, and 8.1% of patients, respectively ( p  = 0.452). The ratio of stone volume and operative time (efficiency of stone removal) was significantly higher in the large space group compared to the small and medium space groups (0.009 ± 0.003 ml/min, 0.013 ± 0.005 ml/min, 0.027 ± 0.012 ml/min, respectively; p  &lt; 0.001). Conclusion Our findings that gaps &gt; 0.6 mm (1.8 Fr), including the combination of a 9.5-Fr UAS and a small caliber ureteroscope, improve SF rates, and larger gaps facilitate stone removal efficiency providing the basis for future development of clinical protocols aimed at improving outcomes.</description><identifier>ISSN: 0724-4983</identifier><identifier>EISSN: 1433-8726</identifier><identifier>DOI: 10.1007/s00345-020-03459-7</identifier><identifier>PMID: 32986134</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Aged ; Calculi ; Computed tomography ; Female ; Humans ; Kidney Calculi - surgery ; Kidney stones ; Lithiasis ; Male ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Nephrolithiasis ; Nephrology ; Oncology ; Original Article ; Patients ; Retrospective Studies ; Sheaths ; Treatment Outcome ; Ureteroscopes ; Ureteroscopy - instrumentation ; Ureteroscopy - methods ; Urology</subject><ispartof>World journal of urology, 2021-07, Vol.39 (7), p.2733-2739</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2020</rights><rights>2020. Springer-Verlag GmbH Germany, part of Springer Nature.</rights><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-1cfcd82ffc81456d544f5a63d32cdc2e002da0a7061106aea0ccfc4799f94fd33</citedby><cites>FETCH-LOGICAL-c375t-1cfcd82ffc81456d544f5a63d32cdc2e002da0a7061106aea0ccfc4799f94fd33</cites><orcidid>0000-0002-0744-7492</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32986134$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Komeya, Mitsuru</creatorcontrib><creatorcontrib>Odaka, Hisakazu</creatorcontrib><creatorcontrib>Watanabe, Takahiko</creatorcontrib><creatorcontrib>Kiuchi, Hirokazu</creatorcontrib><creatorcontrib>Ogawa, Takehiko</creatorcontrib><creatorcontrib>Yao, Masahiro</creatorcontrib><creatorcontrib>Matsuzaki, Junichi</creatorcontrib><title>Gap between UAS and ureteroscope predicts renal stone-free rate after flexible ureteroscopy with the fragmentation technique</title><title>World journal of urology</title><addtitle>World J Urol</addtitle><addtitle>World J Urol</addtitle><description>Purpose To assess the effect of our new classification on surgical outcomes after flexible ureteroscopy (fURS) for kidney stones. Methods We retrospectively examined 128 patients after single renal fURS procedures performed using ureteral access sheaths (UASs) with the fragmentation technique. Based on the gap (calculated by subtracting the ureteroscope diameter from the UAS diameter), enrolled patients were divided into three groups: small (&lt; 0.6 mm), medium (0.6 to &lt; 1.2 mm), and large space groups (≥ 1.2 mm). Stone-free (SF) status was defined as either complete absence of stones (SF) or the presence of stones &lt; 4 mm in diameter on non-contrast computed tomography (NCCT). Results The SF rate was significantly lower in the small space group (50% in small, 97.9% in medium, 89.2% in large; p  = 0.001). Perioperative complications over Clavien–Dindo Grade I were observed in 16.7%, 4.2%, and 8.1% of patients, respectively ( p  = 0.452). The ratio of stone volume and operative time (efficiency of stone removal) was significantly higher in the large space group compared to the small and medium space groups (0.009 ± 0.003 ml/min, 0.013 ± 0.005 ml/min, 0.027 ± 0.012 ml/min, respectively; p  &lt; 0.001). 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Methods We retrospectively examined 128 patients after single renal fURS procedures performed using ureteral access sheaths (UASs) with the fragmentation technique. Based on the gap (calculated by subtracting the ureteroscope diameter from the UAS diameter), enrolled patients were divided into three groups: small (&lt; 0.6 mm), medium (0.6 to &lt; 1.2 mm), and large space groups (≥ 1.2 mm). Stone-free (SF) status was defined as either complete absence of stones (SF) or the presence of stones &lt; 4 mm in diameter on non-contrast computed tomography (NCCT). Results The SF rate was significantly lower in the small space group (50% in small, 97.9% in medium, 89.2% in large; p  = 0.001). Perioperative complications over Clavien–Dindo Grade I were observed in 16.7%, 4.2%, and 8.1% of patients, respectively ( p  = 0.452). The ratio of stone volume and operative time (efficiency of stone removal) was significantly higher in the large space group compared to the small and medium space groups (0.009 ± 0.003 ml/min, 0.013 ± 0.005 ml/min, 0.027 ± 0.012 ml/min, respectively; p  &lt; 0.001). Conclusion Our findings that gaps &gt; 0.6 mm (1.8 Fr), including the combination of a 9.5-Fr UAS and a small caliber ureteroscope, improve SF rates, and larger gaps facilitate stone removal efficiency providing the basis for future development of clinical protocols aimed at improving outcomes.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>32986134</pmid><doi>10.1007/s00345-020-03459-7</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-0744-7492</orcidid></addata></record>
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source Springer Nature
subjects Adult
Aged
Calculi
Computed tomography
Female
Humans
Kidney Calculi - surgery
Kidney stones
Lithiasis
Male
Medicine
Medicine & Public Health
Middle Aged
Nephrolithiasis
Nephrology
Oncology
Original Article
Patients
Retrospective Studies
Sheaths
Treatment Outcome
Ureteroscopes
Ureteroscopy - instrumentation
Ureteroscopy - methods
Urology
title Gap between UAS and ureteroscope predicts renal stone-free rate after flexible ureteroscopy with the fragmentation technique
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