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External limiting membrane angle as a composite predictive index for post-operative ELM closure in full thickness macular holes

Aim To evaluate pre-operative qualitative and quantitative parameters of external limiting membranes (ELM) and other associated full thickness macular holes (FTMH) features and their predictive values for post-operative anatomical and functional outcomes. Methods This was a retrospective study of 48...

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Published in:Graefe's archive for clinical and experimental ophthalmology 2020-12, Vol.258 (12), p.2603-2609
Main Authors: Nair, Unnikrishnan, Menon, Rahul R, Mohan, Ashwin, Vijayan, Amritha, Indurkar, Asmita, Soman, Manoj
Format: Article
Language:English
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Summary:Aim To evaluate pre-operative qualitative and quantitative parameters of external limiting membranes (ELM) and other associated full thickness macular holes (FTMH) features and their predictive values for post-operative anatomical and functional outcomes. Methods This was a retrospective study of 48 eyes that underwent vitrectomy with internal limiting membrane (ILM) peeling for FTMH and had type 1 closure. All subjects underwent optical coherence tomography (SDOCT, Heidelberg, Spectralis), and the eyes were divided into complete ELM closure (CEC) and incomplete ELM closure (IEC) groups based on the post-operative OCTs within 2 months, and ROC curves were used to estimate which of the pre-operative parameters could best predict eyes falling in the CEC group. Results The mean pre-op ELM defect was smaller in CEC group (594 μm vs 1126 μm, p  
ISSN:0721-832X
1435-702X
DOI:10.1007/s00417-020-04949-5