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Delayed matching to sample task 48: assessment of malingering with simulating design

The results of neuropsychological tests may be distorted by patients who exaggerate cognitive deficits. Eighty-three patients with cognitive deficit [Amnestic Mild Cognitive Impairment (aMCI), n = 53; Alzheimer's disease (AD) dementia, n = 30], 44 healthy older adults (HA), and 30 simulators of...

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Bibliographic Details
Published in:Aging, Neuropsychology, and Cognition Neuropsychology, and Cognition, 2021-11, Vol.28 (6), p.797-811
Main Authors: Nikolai, T., Cechova, K., Bukacova, K., Fendrych Mazancova, A., Markova, H., Bezdicek, O., Hort, J., Vyhnalek, M.
Format: Article
Language:English
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Summary:The results of neuropsychological tests may be distorted by patients who exaggerate cognitive deficits. Eighty-three patients with cognitive deficit [Amnestic Mild Cognitive Impairment (aMCI), n = 53; Alzheimer's disease (AD) dementia, n = 30], 44 healthy older adults (HA), and 30 simulators of AD (s-AD) underwent comprehensive neuropsychological assessment. Receiver Operating Characteristic (ROC) analysis revealed high specificity but low sensitivity of the Delayed Matching to Sample Task (DMS48) in differentiating s-AD from AD dementia (87 and 53%, respectively) and from aMCI (96 and 57%). The sensitivity was considerably increased by using the DMS48/Rey Auditory Verbal Learning Test (RAVLT) ratio (specificity and sensitivity 93% and 93% for AD dementia and 96% and 80% for aMCI). The DMS48 differentiates s-AD from both aMCI and AD dementia with high specificity but low sensitivity. Its predictive value greatly increased when evaluated together with the RAVLT.
ISSN:1382-5585
1744-4128
DOI:10.1080/13825585.2020.1826898