3D Bioprinting-Tunable Small-Diameter Blood Vessels with Biomimetic Biphasic Cell Layers

Blood vessel damage resulting from trauma or diseases presents a serious risk of morbidity and mortality. Although synthetic vascular grafts have been successfully commercialized for clinical use, they are currently only readily available for large-diameter vessels (>6 mm). Small-diameter vessel...

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Bibliographic Details
Published in:ACS applied materials & interfaces 2020-10, Vol.12 (41), p.45904-45915
Main Authors: Zhou, Xuan, Nowicki, Margaret, Sun, Hao, Hann, Sung Yun, Cui, Haitao, Esworthy, Timothy, Lee, James D, Plesniak, Michael, Zhang, Lijie Grace
Format: Article
Language:English
Subjects:
Biological and Medical Applications of Materials and Interfaces
Biomimetic Materials - chemistry
Bioprinting
Blood Vessels - chemistry
Cell Proliferation
Cell Survival
Cells, Cultured
Endothelial Cells - cytology
Humans
Myocytes, Smooth Muscle - cytology
Particle Size
Printing, Three-Dimensional
Surface Properties
Tissue Scaffolds - chemistry
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Summary:Blood vessel damage resulting from trauma or diseases presents a serious risk of morbidity and mortality. Although synthetic vascular grafts have been successfully commercialized for clinical use, they are currently only readily available for large-diameter vessels (>6 mm). Small-diameter vessel (
ISSN:1944-8244
1944-8252
DOI:10.1021/acsami.0c14871