No effect of a low dose of metformin on the lipid profile, body mass index and weight gain in pregnant women with obesity: A randomized trial

Evaluate the lipid profile, Body Mass Index (BMI) and weight gain of pregnant women with obesity and the effect of a low dose (1000 mg/day) of metformin hydrochloride on these parameters. A randomized clinical trial was performed from October 31th, 2014 to January 25th, 2018 with pregnant women diag...

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Bibliographic Details
Published in:Obesity research & clinical practice 2020-11, Vol.14 (6), p.561-565
Main Authors: Dienstmann, Guilherme, Nascimento, Iramar Baptistella do, Sales, Willian Barbosa, Leite Ramos de Souza, Matheus, Silva, Grazielle Dutra da, de Oliveira, Larissa Cano, Silva, Jean Carl
Format: Article
Language:English
Subjects:
Lipoprotein
Metformin
Obesity
Pregnancy
Triglycerides
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Summary:Evaluate the lipid profile, Body Mass Index (BMI) and weight gain of pregnant women with obesity and the effect of a low dose (1000 mg/day) of metformin hydrochloride on these parameters. A randomized clinical trial was performed from October 31th, 2014 to January 25th, 2018 with pregnant women diagnosed with obesity by arrival BMI ≥ 30.0 kg/m2. The participants were randomized into two groups: metformin and control. All pregnant women received standard prenatal follow-up and the same instructions of diet and physical exercise. Laboratory tests were performed at three different times: first moment with gestational age (GA) 
ISSN:1871-403X
1878-0318
DOI:10.1016/j.orcp.2020.09.005