Human parvovirus 4: An emerging etiological agent in cases presenting with influenza like illness

This study was planned to study the association of parvovirus 4 (PARV4) with Influenza‐like illness (ILI). A total of 1111 patients with a clinical diagnosis of ILI and 220 healthy controls were tested for Influenza A/HINI/and H3N2, Influenza B, and PARV4. Further sequencing was done to analyze the...

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Bibliographic Details
Published in:Journal of medical virology 2021-08, Vol.93 (8), p.5158-5162
Main Authors: Prakash, Shantanu, Shukla, Suruchi, Bhagat, Amit K., Mishra, Hricha, Vangala, Ramakrishna, Jain, Amita
Format: Article
Language:English
Subjects:
disease association
Etiology
genotype
Genotype & phenotype
Genotypes
Illnesses
Influenza
Influenza A
Influenza B
influenza like illness (ILI)
influenza virus
Parvovirus 4
Parvoviruses
Risk management
Virology
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Summary:This study was planned to study the association of parvovirus 4 (PARV4) with Influenza‐like illness (ILI). A total of 1111 patients with a clinical diagnosis of ILI and 220 healthy controls were tested for Influenza A/HINI/and H3N2, Influenza B, and PARV4. Further sequencing was done to analyze the genotype distribution of parvovirus 4. Influenza A/HINI, A/H3N2, and B were detected in 334 (30.06%), 9 (0.81%), and 10 (0.9%) cases respectively. PARV4 was detected in 135 (12.15%) cases and one healthy control. Parvovirus 4 was significantly higher in cases as compared to controls (relative risk, 30.77%; p 
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.26579