Disease severity affects myocardial functions in patients with treatment‐naive early rheumatoid arthritis

Objectives The cross‐sectional study aimed to assess myocardial functions using global longitudinal strain (GLS) echocardiography and arrhythmia parameters with treatment naive newly diagnosed rheumatoid arthritis (RA) and no clinical evidence of cardiovascular disease (CVD). Methods Seventy seven n...

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Bibliographic Details
Published in:International journal of rheumatic diseases 2021-04, Vol.24 (4), p.494-501
Main Authors: Çakmak, Ender Özgün, Fındıkçıoğlu, Uğur, Tezcan, Mehmet Engin
Format: Article
Language:English
Subjects:
Arrhythmia
Cardiac arrhythmia
Cardiovascular diseases
Citrulline
cQT
disease severity
Echocardiography
EKG
global longitudinal strain
Patients
Rheumatoid arthritis
Rheumatoid factor
Tp‐e/cQT
Ventricle
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Summary:Objectives The cross‐sectional study aimed to assess myocardial functions using global longitudinal strain (GLS) echocardiography and arrhythmia parameters with treatment naive newly diagnosed rheumatoid arthritis (RA) and no clinical evidence of cardiovascular disease (CVD). Methods Seventy seven newly diagnosed treatment‐naive RA patients were enrolled. Disease severity was evaluated according to rheumatoid factor (RF) and anti‐citrullinated protein antibodies (ACPA) positivity, and Disease Activity Score 28 C‐reactive protein (DAS28 CRP). Myocardial functions were assessed using conventional echocardiography and GLS technique and electrocardiogram parameters cQT and Tp‐e/cQT. Results Twenty three patients had severe disease while 54 patients were non‐severe. The Left Ventricle GLS (17.98 ± 1.24 vs 21.29 ± 1.03, P 
ISSN:1756-1841
1756-185X
DOI:10.1111/1756-185X.13992