Longitudinal evolution of non-motor symptoms according to age at onset in early Parkinson's disease

To investigate the longitudinal change of non-motor symptoms according to the age at onset in Parkinson's disease (PD). This cohort study using the Parkinson's Progression Markers Initiative data included 405 patients with early PD. They were classified into late-onset (age at onset ≥ 70 y...

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Bibliographic Details
Published in:Journal of the neurological sciences 2020-11, Vol.418, p.117157-117157, Article 117157
Main Authors: Kim, Ryul, Shin, Jung Hwan, Park, Sangmin, Kim, Han-Joon, Jeon, Beomseok
Format: Article
Language:English
Subjects:
Age at onset
Age of Onset
Aged
Anxiety - epidemiology
Cognitive Dysfunction - diagnosis
Cognitive Dysfunction - epidemiology
Cohort Studies
Humans
Late-onset
Non-motor symptom
Parkinson Disease - complications
Parkinson Disease - epidemiology
Parkinson's disease
Young-onset
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Summary:To investigate the longitudinal change of non-motor symptoms according to the age at onset in Parkinson's disease (PD). This cohort study using the Parkinson's Progression Markers Initiative data included 405 patients with early PD. They were classified into late-onset (age at onset ≥ 70 years, n = 63), middle-onset (50 to 69 years, n = 268), and young-onset (
ISSN:0022-510X
1878-5883
DOI:10.1016/j.jns.2020.117157