Biomineralization: An Opportunity and Challenge of Nanoparticle Drug Delivery Systems for Cancer Therapy

Biomineralization is a common process in organisms to produce hard biomaterials by combining inorganic ions with biomacromolecules. Multifunctional nanoplatforms are developed based on the mechanism of biomineralization in many biomedical applications. In the past few years, biomineralization‐based...

Full description

Saved in:
Bibliographic Details
Published in:Advanced healthcare materials 2020-11, Vol.9 (22), p.e2001117-n/a
Main Authors: Wang, Weicai, Liu, Xiaofan, Zheng, Xiangjiang, Jin, Hyung Jong, Li, Xuemei
Format: Article
Language:English
Subjects:
Biocompatibility
Biomaterials
Biomedical materials
Biomineralization
Cancer
Cancer therapies
cancer therapy
Degradability
Drug delivery
Drug Delivery Systems
Drug development
inorganic materials
Mineralization
Nanomaterials
Nanoparticles
Nanostructures
Nanotechnology
Neoplasms - drug therapy
organic templates
Theranostic Nanomedicine
Therapy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Biomineralization is a common process in organisms to produce hard biomaterials by combining inorganic ions with biomacromolecules. Multifunctional nanoplatforms are developed based on the mechanism of biomineralization in many biomedical applications. In the past few years, biomineralization‐based nanoparticle drug delivery systems for the cancer treatment have gained a lot of research attention due to the advantages including simple preparation, good biocompatibility, degradability, easy modification, versatility, and targeting. In this review, the research trends of biomineralization‐based nanoparticle drug delivery systems and their applications in cancer therapy are summarized. This work aims to promote future researches on cancer therapy based on biomineralization. Rational design of nanoparticle drug delivery systems can overcome the bottleneck in the clinical transformation of nanomaterials. At the same time, biomineralization has also provided new research ideas for cancer treatment, i.e., targeted therapy, which has significantly better performance. Biomineralization is a common process in organisms to produce hard biomaterials by combining inorganic ions with biomacromolecules. In the past few years, biomineralization‐based nanoparticle drug delivery systems for cancer treatment have gained a lot of research attention due to the advantages including good biocompatibility, degradability, and targeting. This work aims to promote future researches on cancer therapy based on biomineralization.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.202001117