Bilateral extracranial extension of giant somatotropic pituitary adenoma after combined treatment. Two-stage gamma knife radiosurgery as a solution

•Pituitary adenoma can invade not only cavernous sinus but grow through cranial foramina.•Absence of intracranial growth after irradiation does not exclude extracranial expansion.•Extracranial pituitary adenoma can have no neurological signs.•Gamma knife SRS for pituitary adenoma in the subtemporal...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2020-11, Vol.198, p.106245-106245, Article 106245
Main Authors: Rak, V.A., Evdokimova, O.L., Stepanov, V.N., Godkov, I.M., Tokarev, A.S.
Format: Article
Language:English
Subjects:
Adenoma
Chemotherapy
gamma knife
Growth hormones
Magnetic resonance imaging
Pituitary
pituitary adenoma
Radiation therapy
Radiosurgery
Sinuses
subtemporal fossa
Surgery
Toxicity
Tumors
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Description
Summary:•Pituitary adenoma can invade not only cavernous sinus but grow through cranial foramina.•Absence of intracranial growth after irradiation does not exclude extracranial expansion.•Extracranial pituitary adenoma can have no neurological signs.•Gamma knife SRS for pituitary adenoma in the subtemporal fossa is safe for cranial nerves and decreases hormonal secretion.
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2020.106245