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Bilateral extracranial extension of giant somatotropic pituitary adenoma after combined treatment. Two-stage gamma knife radiosurgery as a solution

•Pituitary adenoma can invade not only cavernous sinus but grow through cranial foramina.•Absence of intracranial growth after irradiation does not exclude extracranial expansion.•Extracranial pituitary adenoma can have no neurological signs.•Gamma knife SRS for pituitary adenoma in the subtemporal...

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Published in:Clinical neurology and neurosurgery 2020-11, Vol.198, p.106245-106245, Article 106245
Main Authors: Rak, V.A., Evdokimova, O.L., Stepanov, V.N., Godkov, I.M., Tokarev, A.S.
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container_title Clinical neurology and neurosurgery
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creator Rak, V.A.
Evdokimova, O.L.
Stepanov, V.N.
Godkov, I.M.
Tokarev, A.S.
description •Pituitary adenoma can invade not only cavernous sinus but grow through cranial foramina.•Absence of intracranial growth after irradiation does not exclude extracranial expansion.•Extracranial pituitary adenoma can have no neurological signs.•Gamma knife SRS for pituitary adenoma in the subtemporal fossa is safe for cranial nerves and decreases hormonal secretion.
doi_str_mv 10.1016/j.clineuro.2020.106245
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source ScienceDirect Journals
subjects Adenoma
Chemotherapy
gamma knife
Growth hormones
Magnetic resonance imaging
Pituitary
pituitary adenoma
Radiation therapy
Radiosurgery
Sinuses
subtemporal fossa
Surgery
Toxicity
Tumors
title Bilateral extracranial extension of giant somatotropic pituitary adenoma after combined treatment. Two-stage gamma knife radiosurgery as a solution
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