Extricating the Association Between the Prognostic Factors of Colorectal Cancer

Purpose Colorectal cancer (CRC) is one of the recurring and lethal gastrointestinal tract disease rankings as the primary cause of worldwide morbidity and mortality. In general, the tumour node metastasis (TNM) and Dukes classification assist in diagnosis, prognosis and treatments of CRC along with...

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Bibliographic Details
Published in:Journal of gastrointestinal cancer 2021-09, Vol.52 (3), p.1022-1028
Main Authors: Mohd, Younis, Balasubramanian, Balamuralikrishnan, Meyyazhagan, Arun, Kuchi Bhotla, Haripriya, Shanmugam, Suresh Kumar, Ramesh Kumar, Mithun Kumar, Pappusamy, Manikantan, Alagamuthu, Karthick Kumar, Keshavarao, Sasikala, Arumugam, Vijaya Anand
Format: Article
Language:English
Subjects:
Adult
Aged
Cancer Research
Colorectal Neoplasms - blood
Colorectal Neoplasms - epidemiology
Colorectal Neoplasms - pathology
Female
Gastroenterology
Humans
India - epidemiology
Internal Medicine
Lymphatic Metastasis - pathology
Male
Medicine
Medicine & Public Health
Middle Aged
Neoplasm Grading - statistics & numerical data
Neoplasm Staging - statistics & numerical data
Oncology
Original Research
Prognosis
Radiotherapy
Risk Factors
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Summary:Purpose Colorectal cancer (CRC) is one of the recurring and lethal gastrointestinal tract disease rankings as the primary cause of worldwide morbidity and mortality. In general, the tumour node metastasis (TNM) and Dukes classification assist in diagnosis, prognosis and treatments of CRC along with haematological examinations and tumour demographic characterisations in patients. Methods The present investigation is carried out on clinically acknowledged sixty-five CRC patients based on haematological findings and are sorted into stages using TNM and Dukes. The present study is to find the association between haematological findings, demographic characters, differentiation position, lymph node invasion and tumour node metastasis in CRC patients in accordance with their age. Results We observed significant ( p < 0.05) nexus between lymph node metastasis and tumour node metastasis on the basis of tumour’s differentiation demographic positioning and age of the individuals. Conclusion Earlier location tracing and medicinal treatment or surgery lessen the chance of CRC morbidity and mortality along with prolonging survival rate via prognostic factors and disease position determination.
ISSN:1941-6628
1941-6636
DOI:10.1007/s12029-020-00535-4