Contemporary Trends in Presentation and Management of Spermatocytic Seminoma

To characterize the presentation and management of spermatocytic seminoma (SS) compared to classic seminoma in adults utilizing a large cancer registry. Patients >18 years of age in the National Cancer Database from 2006 to 2016 who underwent orchiectomy for testicular tumors were identified. Dem...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2020-12, Vol.146, p.177-182
Main Authors: Patel, Parth M., Patel, Hiten D., Koehne, Elizabeth L., Doshi, Chirag, Belshoff, Alex, Seffren, Christopher M., Baker, Marshall, Gorbonos, Alex, Gupta, Gopal
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Chemotherapy, Adjuvant - statistics & numerical data
Chemotherapy, Adjuvant - trends
Humans
Lymph Node Excision
Male
Middle Aged
Neoplasm Staging
Orchiectomy - statistics & numerical data
Orchiectomy - trends
Radiotherapy, Adjuvant - statistics & numerical data
Radiotherapy, Adjuvant - trends
Registries - statistics & numerical data
Risk Factors
Seminoma - diagnosis
Seminoma - mortality
Seminoma - pathology
Seminoma - therapy
Survival Rate
Testicular Neoplasms - diagnosis
Testicular Neoplasms - mortality
Testicular Neoplasms - pathology
Testicular Neoplasms - therapy
Treatment Outcome
United States - epidemiology
Watchful Waiting - statistics & numerical data
Watchful Waiting - trends
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Summary:To characterize the presentation and management of spermatocytic seminoma (SS) compared to classic seminoma in adults utilizing a large cancer registry. Patients >18 years of age in the National Cancer Database from 2006 to 2016 who underwent orchiectomy for testicular tumors were identified. Demographics, oncologic characteristics, and treatment patterns were compared between patients with SS and classic seminoma. Of 53,481 adults receiving orchiectomy, 29,208 were diagnosed with classic seminoma and 299 (1%) with SS. Compared to patients with classic seminoma, SS patients were older (57 vs 39 years) and more likely to be African-American (odds ratio (OR) 1.8) and insured by Medicare (OR 2.0; all P 6 cm: OR 1.8), but were less likely to have ≥pT2 stage (OR 0.5), regional nodal involvement (Clinical Stage II: OR 0.3), or distant metastatic disease (Clinical Stage III: OR 0.1; all P
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2020.10.002