Longitudinal study of neuropathic pain in patients with Guillain-Barré syndrome

Objective The aim of this study was to analyze neuropathic pain (NeP) and its therapy in patients with Guillain-Barré syndrome (GBS) during a 6-month follow-up period. Method This longitudinal multicenter study included 69 newly diagnosed adult GBS patients. NeP diagnosis was based on the criteria o...

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Bibliographic Details
Published in:Irish journal of medical science 2021-08, Vol.190 (3), p.1137-1142
Main Authors: Vukojevic, Zoran, Berisavac, Ivana, Bozovic, Ivo, Dominovic-Kovacevic, Aleksandra, Lavrnic, Dragana, Peric, Stojan
Format: Article
Language:English
Subjects:
Family Medicine
General Practice
Internal Medicine
Medicine
Medicine & Public Health
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Summary:Objective The aim of this study was to analyze neuropathic pain (NeP) and its therapy in patients with Guillain-Barré syndrome (GBS) during a 6-month follow-up period. Method This longitudinal multicenter study included 69 newly diagnosed adult GBS patients. NeP diagnosis was based on the criteria of Finnerup and confirmed by the PainDETECT Questionnaire (PD-Q). Severity of GBS was assessed by GBS disability scale (GDS). Patients were assessed: on day 14 (D14), day 28 (D28), month 3 (M3), and month 6 (M6) from the disease onset. Results At D14, pain was present in 85.5% of patients, while 26.4% had NeP. At M6, 72.5% of patients had pain, 20.0% of them NeP. In acute GBS, pain intensity was higher in patients with NeP compared to those with non-NeP ( p  
ISSN:0021-1265
1863-4362
DOI:10.1007/s11845-020-02395-0