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Association of elevated neonatal thyroid-stimulating hormone levels with school performance and stimulant prescription for attention deficit hyperactivity disorder in childhood

Untreated severe newborn thyroid deficiency causes neurocognitive impairment; however, the impact of mild thyroid deficiency is not known. This study aimed to examine whether mildly elevated neonatal thyroid-stimulating hormone (TSH) levels are associated with poor school performance or stimulant pr...

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Bibliographic Details
Published in:European journal of pediatrics 2021-04, Vol.180 (4), p.1073-1080
Main Authors: Lain, Samantha J., Wiley, Veronica, Jack, Michelle, Martin, Andrew J., Wilcken, Bridget, Nassar, Natasha
Format: Article
Language:English
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Summary:Untreated severe newborn thyroid deficiency causes neurocognitive impairment; however, the impact of mild thyroid deficiency is not known. This study aimed to examine whether mildly elevated neonatal thyroid-stimulating hormone (TSH) levels are associated with poor school performance or stimulant prescription for attention deficit hyperactivity disorder (ADHD). This record-linkage study included 232,790 term-born infants in Australia with a TSH level below newborn screening threshold (
ISSN:0340-6199
1432-1076
DOI:10.1007/s00431-020-03828-9