Prognostic nutritional index predicts in-hospital mortality in patients with acute Stanford type A aortic dissection

• Published in: Perfusion 2021-10, Vol.36 (7), p.710-716
• Main Authors: Keskin, Hasan Attila, Kurtul, Alparslan, Esenboğa, Kerim, Çiçek, Mustafa Cüneyt, Katırcıoğlu, Salih Fehmi
• Format: Article
• Language: English
• Subjects: Aged; Aneurysm, Dissecting - surgery; Aorta; Aortic dissection; Cell number; Dimers; Dissection; Emergency medical services; Female; Hospital Mortality; Humans; Inflammation; Lymphocytes; Male; Mathematical analysis; Medical records; Middle Aged; Mortality; Multivariate analysis; Nutrition Assessment; Nutritional Status; Patients; Prognosis; Retrospective Studies; Risk analysis; Risk factors; Serum albumin; Survival
• ISSN: 0267-6591; 1477-111X
• DOI: 10.1177/0267659120961937

Background: Acute Stanford type A aortic dissection (ATAAD) is a life-threatening medical emergency. The aim of this study was to investigate the clinical significance of the prognostic nutritional index (PNI) as a novel inflammatory marker for ATAAD patients undergoing surgical repair. Methods: We retrospectively examined the medical records of 151 ATAAD patients who treated surgically. Patients were divided into two groups (survival and death) and these groups were compared with respect to clinical and laboratory parameters. The PNI was calculated as 10 × serum albumin (g/dL) + 0.005 × total lymphocyte count (per mm3). Logistic regression analyses were performed to identify the risk factors of in-hospital mortality. Results: The mean age of the study cohort was 61 ± 12 years, 99 (65.6%) were males, and 35 (23.2%) patients died during the hospital stay. The PNI levels were significantly lower in death group compared with survival group (32.80 ± 4.90 vs. 37.94 ± 5.42, p