Viscoelastic testing in benign hematologic disorders: Clinical perspectives and future implications of point‐of‐care testing to assess hemostatic competence

Viscoelastic tests (VETs) have been used routinely for liver transplantation, cardiac surgery, and trauma, but only recently have found clinical utility in benign hematologic disorders. Therefore, guidelines for diagnosis and treatment of these disorders based on viscoelastic variables have been ada...

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Bibliographic Details
Published in:Transfusion (Philadelphia, Pa.) Pa.), 2020-10, Vol.60 (S6), p.S101-S121
Main Authors: Speybroeck, Jacob, Marsee, Mathew, Shariff, Faadil, Zackariya, Nuha, Grisoli, Anne, Lune, Stefani Vande, Larson, Emilee E., Hatch, Jordan, McCauley, Ross, Shariff, Faisal, Aversa, John G., Son, Michael, Agostini, Vanessa, Campello, Elena, Simioni, Paolo, Scărlătescu, Escaterina, Kwaan, Hau, Hartmann, Jan, Fries, Dietmar, Walsh, Mark
Format: Article
Language:English
Subjects:
Benign
Diagnosis
Diagnostic systems
Disorders
Health services
Heart surgery
Hematological diseases
Liver transplantation
Medical diagnosis
Resuscitation
Surgery
Transplantation
Transplants & implants
Trauma
Viscoelasticity
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Summary:Viscoelastic tests (VETs) have been used routinely for liver transplantation, cardiac surgery, and trauma, but only recently have found clinical utility in benign hematologic disorders. Therefore, guidelines for diagnosis and treatment of these disorders based on viscoelastic variables have been adapted from the existing transplant, cardiothoracic surgery, and trauma resuscitation literature. As a result, diagnostic and therapeutic strategies for benign hematologic disorders utilizing VETs are not uniform. Accordingly, even though there has been a recent increase in the utilization of VET for the diagnosis and treatment of such disorders, the literature is still in its early stages. Analysis of point‐of‐care viscoelastic tracings from benign hematologic disorders has the potential to allow prompt recognition of disease and to guide patient‐specific intervention. Here we present a review describing the application of VETs to benign hematologic disorders.
ISSN:0041-1132
1537-2995
DOI:10.1111/trf.16088